Kanada Lokaci 2022-01-24, Rhovac, wani kamfanin magunguna ya mayar da hankali kan tumo na jiki, ya sanar da cewa aikace-aikacen lambobinsa RV001 PTTAFEPLEID Ciwon Ikklesiya ya ba shi izini (Cipo). A baya can, kamfanin ya samu kayan kwalliya da suka danganci RV001 a Amurka, Turai da Japan. Wannan tallafin Patent zai samar da kariya ga RV001 a cikin manyan kasuwanni da kuma ta daukaka shinge na kamfanin.
Kamar aikace-aikacen tasha na aikace-aikacen da aka bayar a baya, wannan kayan aikin ya rufe maganin rigakafin cutar RV001 da kuma bambance-bambancen sa, da kuma amfani a cikin cutar kansa / rigakafin Rhoc-bayyana cutar kansa. Daga gare su, Rhoc kamu ne na tumo mai alaƙa (taa) wanda yake wuce gona da iri a cikin nau'ikan tumo daban-daban. Da zarar an ba da izini, patent zai ƙare a 2028-12 kuma ana tsammanin zai sami takardar shaidar ƙarin kariya (CSP).
01 Onilcamotide
Onilcamotide shine maganin rigakafi na mahaifa wanda ya samo asali daga dangin Hommanous wanda zai iya zama - 51, wanda ake iya ɗaukar rigakafi da kayan rigakafi da kuma mahimman ayyukan. Kungiyar Harkokin Kasa ta Onilcamotide tana karfafa tsarin garkuwar jiki don hawa mai wahala (CTL) da martani na Rhoc-expressing, don haka lesing da tumo.
2020-11, an ba RV001 da sauri da FDA.
02 gwaji na asibiti 02
A shekara ta 2018, gwajin lokaci na I / IIA Clinical fitina ta Oneilcamotide don lura da cutar sankarar cutar kansa, kuma jimlar marasa lafiya 21 ne suka yi rajista. Sakamakon ya nuna cewa Oneilcamotide ya kasance lafiya kuma an jure shi sosai. Bugu da kari, marasa lafiya sun kirkiro da martani mai ƙarfi da kuma yawan amsawa mai ƙarfi na gaba. A shekarar 2021, sakamakon biyo na 19 na waɗannan batutuwa, shekaru uku bayan kammala jiyya ko ba su da cigaba da takamaiman cigaba (PSAWA). . Daga cikin waɗannan, batutuwa 16 ba su da ɓarna na PSSA, kuma wasu batutuwa 3 suna da jinkirin PSA. PSA ita ce furotin da aka samar ta hanyar ciyawar prostate kuma ana amfani dashi don bin diddigin ci gaban cutar kansa.
A cikin 2019, Clinical Clinical Bravac (bazuwar, makafi biyu, an shirya shi biyu don kimanta kan cutar kansa ko kuma iyakance ci gaban ciwon kansa na cutar kansa bayan tiyata / radiation. Wannan gwajin ISI na IIB wani binciken kasa da kasa ne, daultican da yawa na daukar batutuwa a cikin kasashen Turai 6 (Denmark, Finland, Sweden, Jamus, Jamus, da Amurka. Gwajin ya gama daukar ma'aikata a cikin 2021-09, tare da duka kimanin batutuwa 175 rijista, kuma zai ƙare a 2022h1. Bugu da kari, Rhovac yana shirin gudanar da bincike na bincike game da ingantaccen shaidar alamomi na RV001 a cikin nuni.
Bugu da kari, kwamitin kula da kula da tsaro na tsaro na RV001 a shekarar 2021-07, kuma ba a yi amfani da abubuwan da ba a tsammani ba, wanda ya yi daidai da sakamakon asibiti na baya / ii sakamakon.
Lokaci: Feb-17-2022