Suna | Orlistat |
Lambar CAS | 96829-58 |
Tsarin kwayoyin halitta | C29H53No5 |
Nauyi na kwayoyin | 495.73 |
Lambar Einecs | 639-755-1 |
Mallaka | <50 ° C |
Yawa | 0.976 ± 0.06G / cm3 (annabta) |
Yanayin ajiya | 2-8 ° C |
Fom | Foda |
Launi | Farin launi |
Acidarancin acid | (Pka) 14.59 ± 0.23 (annabta) |
(S) -2-frofylamano-4-methyl-pentanoicacid (s) -1 - [(2s, 3s) -3 Ormyl-l-leucine (1s) -1 - [((2s, 3s) -3-hexyl-4-oxetyl-4-oxetyl-4-oxetates
Kaddarorin
Farin Crystalline foda, kusan insolable a cikin ruwa, mai sauƙin narkewa a cikin methanol da etholyze, melyze aya shine 40 ℃ ~ 42 ℃. Kemukanta ne mai ilimin sihirin da ke dauke da matakai hudu masu kyan gani, a wani zazzabi na 529nm, maganinta na tabo na gani.
Yanayin aiki
Orlistat mai dadewa ne mai aiki da karfi da kuma mai amfani da gastrointes na jijiyoyin ciki wanda ke sama da enzenmes biyu na sama ta hanyar samar da hadin gwiwa na Lipase a cikin ciki da ƙananan hanji. Enzymes inacymes ba zai iya rushe kitse cikin abinci ba da acid din kyauta da jiki zai iya tunawa da jiki, ta rage yawan kitse da rage nauyi. Bugu da kari, wasu nazarin sun gano cewa Orliistat yana hana hanzarin hanji ta cholesterol ta hanyar inbhib1 pickc1-kamar1, NPC1L1).
Alamar
Ana nuna wannan samfurin a hade tare da abincin munafukai masu laushi na dogon lokaci na dogon lokaci na dogon lokaci, gami da wadanda ke da abubuwan hadarin da ke hade da kiba. Wannan samfurin yana da iko na dogon lokaci (asarar nauyi, nauyin nauyi da rigakafin sake fitarwa) ingancin sake. Cire Orlistat na iya rage abubuwan da suka shafi haɗari da kuma abin da ke cikin cututtukan da suka shafi su, da nau'in cutar hypercholestermia, hyperininsulinemia, hauhawar jini.
Kwarewar magani
Zai iya rage shan bitamin a, d da E. Ana iya ciyar da shi da wannan samfurin a lokaci guda. Idan kana shan shirye-shirye dauke da bitamin a, d da e (kamar wasu samfuran 2 hours bayan ɗaukar wannan samfurin ko a lokacin kwanciya. Mutanen da ke da nau'in ciwon sukari na iya buƙatar rage kashi na wakilan hancin na baka (misali, sulfylure). Hukumar hadin kai tare da cyclosporyine na iya haifar da raguwa a cikin nazarin plasma na ƙarshen. Babban amfani da Amodarone na iya haifar da rage yawan sha da kuma rage ingancin.