Kayayyaki
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Ste-γ-Glu-AEEA-AEEA-OSU
Ste-γ-Glu-AEEA-AEEA-OSU sinadari ne na roba mai haɗaɗɗiyar ƙwayar cuta wanda aka ƙera don isar da magunguna da aka yi niyya da haɗin gwiwar magungunan-magungunan (ADCs). Yana fasalta wutsiya ta stearoyl (Ste) hydrophobic, γ-glutamyl manufa motif, AEEA spacers don sassauci, da ƙungiyar OSu (NHS ester) don ingantaccen haɗin gwiwa.
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Fmoc-Ile-αMeLeu-Leu-OH
Fmoc-Ile-αMeLeu-Leu-OH wani shingen gini ne na roba mai kariya na tripeptide wanda ke nuna α-methylated leucine, wanda aka saba amfani dashi a ƙirar magungunan peptide don haɓaka kwanciyar hankali na rayuwa da zaɓin mai karɓa.
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Dodecyl Phosphocholine (DPC)
Dodecyl Phosphocholine (DPC) wani wanki ne na roba na roba wanda aka yi amfani dashi sosai a cikin binciken furotin na membrane da tsarin tsarin halitta, musamman a cikin NMR spectroscopy da crystallography.
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N-Acetylneuraminic Acid (Neu5Ac Sialic Acid)
N-Acetylneuraminic Acid (Neu5Ac), wanda aka fi sani da sialic acid, monosaccharide ne na halitta wanda ke faruwa a cikin salon salula da ayyukan rigakafi. Yana taka muhimmiyar rawa wajen siginar tantanin halitta, kariya ta ƙwayoyin cuta, da haɓakar ƙwaƙwalwa.
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Ergothionine
Ergothioneine shine maganin antioxidant wanda aka samo asali na amino acid, wanda aka yi nazari don ƙarfin cytoprotective da kaddarorin tsufa. An haɗa shi ta hanyar fungi da ƙwayoyin cuta kuma yana tarawa a cikin kyallen takarda da aka fallasa ga damuwa na oxidative.
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NMN
Nazarce-nazarce da na ɗan adam na farko sun nuna cewa NMN na iya haɓaka tsawon rai, juriya ta jiki, da aikin fahimi.
Abubuwan API:
Babban tsarki ≥99%
Pharmaceutical-grade, dace da na baki ko allura formulations
Kerarre a ƙarƙashin ma'auni kamar GMP
NMN API shine manufa don amfani a cikin abubuwan haɓaka tsufa, hanyoyin kwantar da hankali, da bincike na tsawon rai.
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Glucagon
Glucagon shine hormone peptide na halitta wanda aka yi amfani dashi azaman magani na gaggawa don tsananin hypoglycemia kuma yayi nazari akan rawar da yake takawa a cikin ƙa'idodin rayuwa, asarar nauyi, da kuma gano abubuwan narkewar abinci.
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Motixafortide
Motixafortide shine peptide antagonist CXCR4 na roba wanda aka haɓaka don tara ƙwayoyin hematopoietic stem cells (HSCs) don dasawa na autologous kuma ana nazarinsa a cikin oncology da immunotherapy.
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Glepaglutide
Glepaglutide analog ne na GLP-2 mai tsayi wanda aka haɓaka don maganin gajeriyar ciwon hanji (SBS). Yana haɓaka haɓakar hanji da haɓaka, yana taimaka wa marasa lafiya rage dogaro ga abinci mai gina jiki na mahaifa.
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Elamipretide
Elamipretide wani tetrapeptide ne na mitochondria wanda aka yi niyya don magance cututtukan da ke haifar da tabarbarewar mitochondrial, gami da na farko na mitochondrial myopathy, ciwo na Barth, da gazawar zuciya.
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Donidalorsen
Donidalorsen API wani maganin antisense oligonucleotide (ASO) ne a ƙarƙashin bincike don maganin angioedema na gado (HAE) da kuma yanayin kumburi masu alaƙa. Ana nazarin shi a cikin mahallin hanyoyin kwantar da hankali na RNA, da nufin rage bayyanar cututtukaplasma prekallikrein(KLKB1 mRNA). Masu bincike suna amfani da Donidalorsen don bincika hanyoyin yin shiru na kwayoyin halitta, magunguna masu dogara da kashi, da kuma kulawa na dogon lokaci na kumburi mai shiga tsakani na bradykinin.
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Fitusiran
Fitusiran API wani ƙaramin RNA ne mai tsoma baki (siRNA) wanda aka bincika da farko a fagen cutar haemophilia da rikicewar coagulation. Yana kaiwa hariAntithrombin (AT ko SERPINC1)kwayoyin halitta a cikin hanta don rage samar da antithrombin. Masu bincike suna amfani da Fitusiran don bincika hanyoyin tsangwama na RNA (RNAi), takamaiman ƙwayoyin halittar hanta, da sabbin dabarun warkewa don sake daidaita coagulation a cikin marasa lafiya na hemophilia A da B, tare da ko ba tare da masu hanawa ba.