Tirzepatide
API ɗin Tirzepatide
Tirzepatide shine peptide na roba mai fashewa wanda ke aiki azaman agonist dual agonist na duka masu karɓar insulinotropic polypeptide (GIP) da glucagon-like peptide-1 (GLP-1). Yana wakiltar sabon nau'in hanyoyin kwantar da hankali na tushen incretin da aka sani da "twincretins", yana ba da ingantaccen sarrafa rayuwa ga marasa lafiya da ke da nau'in ciwon sukari na 2 da kiba.
Ana samar da API ɗinmu na Tirzepatide ta hanyoyin dabarun haɗa sinadarai masu ci gaba, yana tabbatar da tsafta mai ƙarfi, ƙarancin ƙazanta, da ingantaccen daidaiton tsari-zuwa-tsari. Ba kamar peptides da aka samo daga rDNA ba, API ɗinmu na roba ba shi da 'yanci daga sunadaran ƙwayoyin sel da DNA, yana inganta ingantaccen yanayin rayuwa da bin ka'idoji. An inganta tsarin masana'antu don haɓakawa don saduwa da haɓakar buƙatun duniya.
Tsarin Aiki
Tirzepatide yana aiki ta lokaci guda yana ƙarfafa duka GIP da masu karɓa na GLP-1, suna ba da ƙarin sakamako da haɓakawa:
Kunna mai karɓar GIP: yana haɓaka haɓakar insulin kuma yana iya haɓaka haɓakar insulin.
Kunna mai karɓar GLP-1: yana hana sakin glucagon, yana jinkirta zubar da ciki, kuma yana rage ci.
Haɗin ayyukan yana haifar da:
Ingantaccen sarrafa glycemic
Rage nauyin jiki
Ingantacciyar gamsuwa da rage cin abinci
Binciken Clinical & Sakamako
Tirzepatide ya nuna ingancin da ba a taɓa ganin irinsa ba a cikin manyan gwaje-gwajen asibiti da yawa (SURPASS & SURMOUNT jerin):
Babban raguwar HbA1c idan aka kwatanta da GLP-1 RAs (misali, Semaglutide)
Rage nauyi har zuwa 22.5% a cikin marasa lafiya masu kiba - kwatankwacin tiyatar bariatric a wasu lokuta
Saurin farawa na sakamako da ingantaccen sarrafa glycemic akan amfani na dogon lokaci
Ingantattun alamomin cardiometabolic: gami da hawan jini, lipids, da kumburi
Tirzepatide ba wai kawai yana sake fasalin yanayin jiyya don nau'in ciwon sukari na 2 ba amma kuma yana fitowa a matsayin babban zaɓi na warkewa don asarar nauyi na likita da ciwo na rayuwa.
Quality & Biyayya
API ɗinmu Tirzepatide:
Haɗu da ƙa'idodin ingancin duniya (FDA, ICH, EU)
An gwada ta HPLC don ƙananan matakan da aka sani da ƙazanta waɗanda ba a san su ba
Kerarre a ƙarƙashin yanayin GMP tare da cikakkun takaddun tsari
Goyan bayan manyan-sikelin samarwa R&D
