Vancomycin shine maganin rigakafi na glycopeptide da ake amfani dashi don maganin rigakafi
Cikakken Bayani
| Suna | Vancomycin |
| Lambar CAS | 1404-90-6 |
| Tsarin kwayoyin halitta | Saukewa: C66H75Cl2N9O24 |
| Nauyin kwayoyin halitta | 1449.25 |
| Lambar EINECS | 215-772-6 |
| Yawan yawa | 1.2882 (ƙananan ƙididdiga) |
| Indexididdigar refractive | 1.7350 (ƙididdiga) |
| Yanayin ajiya | An rufe shi a bushe, 2-8 ° C |
Makamantu
Vancomycin (baseand/orunspecifiedsalts);VANCOMYCIN; VancomycinBase; (3S,6R,7R,22R,23S,26S,36R,38aR) -3-(2-Amino-2-oxoethyl) -44-[2-O-(3-amino-2, 3,6-trideoxy-3-C-methyl-a-L-lyxo-hexopyranosyl-β-D-glucopyranosyl] -10,19-dichloro-2,3,4,5,6,7,23,24,25,26,36,37,38,38a-tetradecahydro-7 ,22,28,30,32-pentahydroxy-6-[[(2R) -4-methChemicalbookyl-2-(methylamino) -1-oxopentyl] -2,5,24,38,39-pentaoxo-22H-8,11:18,21-Dietheno-23, 36-(iminomethano) -13,16:31,35-dimetheno-1H,16H-[1,6,9] oxadiazacyclohexadecino [4,5-m] [10,2,16] benzoxadiazacyclotetracosine-26-carboxylicacid.
Bayani
Vancomycin shine maganin rigakafi na glycopeptide. Tsarin aikinsa shine ɗaure tare da babban kusanci ga alanylalanine a ƙarshen poly-terminal na precursor peptide na bangon ƙwayoyin ƙwayoyin cuta mai hankali, yana toshe haɗin macromolecular peptidoglycan wanda ya ƙunshi bangon ƙwayoyin ƙwayoyin cuta, wanda ke haifar da Rushewar bangon tantanin halitta yana kashe ƙwayoyin cuta. Vancomycin yana da tasiri ga cututtuka masu tsanani da kwayoyin cutar Gram-positive ke haifar da su, musamman ma wadanda ke haifar da methicillin-resistant Staphylococcus aureus, Staphylococcus epidermidis, da Enterococcus masu jure wa sauran maganin rigakafi ko kuma rashin inganci.
Alamu
Ya iyakance ga cututtuka na tsarin da ke haifar da methicillin-resistant Staphylococcus aureus (MRSA) da cututtuka na hanji da cututtuka na tsarin da ke haifar da Clostridium difficile; Marasa lafiya na penicillin-allergic ba za su iya amfani da penicillins ko cephalosporins a cikin marasa lafiya da ciwon staphylococcal mai tsanani ba, ko waɗanda ke fama da cutar staphylococcal mai tsanani waɗanda suka kasa amsa maganin rigakafi na sama, ana iya amfani da vancomycin. Ana kuma amfani da wannan samfurin don maganin Enterococcus endocarditis da Corynebacterium (Diphtheria-like) endocarditis a cikin mutanen da ke fama da rashin lafiyar penicillin. Jiyya na staphylococcus-induced arteriovenous shunt cututtuka a cikin hemodialysis marasa lafiya rashin lafiyar penicillin da marasa rashin lafiyar penicillin.
![Fmoc-L-Lys[Ste(OtBu)-γ-Glu-(OtBu)-AEEA-AEEA]-OH](https://cdn.globalso.com/gentolexgroup/Glepaglutide9-300x300.png)