Carbetocin don hana cakulan na ciki da kuma bayan haihuwa.
Cikakken Bayani
| Suna | Carbetocin |
| Lambar CAS | 37025-55-1 |
| Tsarin kwayoyin halitta | C45H69N12O12S |
| Nauyi na kwayoyin | 988.17 |
| Lambar Einecs | 253-312-6 |
| Takamaiman juyawa | D -69.0 ° (C = 0.25 a cikin 1M Acetic acid) |
| Tafasa | 1477.9 ± 65.0 ° C (annabta) |
| Yawa | 1.218 ± 0.06 g / cm3 (annabta) |
| Yanayin ajiya | -15 ° C |
| Fom | foda |
Kwatanci
Butyryl-Tyr (ni) -ile-gly-Pro-leu-gly-NH2, (sulfideobondyByr-4-ylands); Butyryl-Tyr (ni) -ile-gly-pro-leu-gly-nh2trifluoroacetattatesalt; (Butyl1, Tyr (ni) 2) -1-carbaoxytocytoxytoc interrifluoroacatesalt; (Butyryl1, Tyr (ni) 2) -Oxytocin; (Butyryl1, Tyr (ni) 2) -Oxytoactrifluoroacetattesalt; Carbetociin; Carbetocintriflotesalt; (2-o-methyltyrosineine) -de-amino-1-carbaoxytocicin
Aikin halittu
Carbetocin, analogatochin (OT) analog, shine oxytocin repawor mai rikicewa tare da Ki na 7.1 nm. Carbetocin yana da babban dangi (KI = 1.17 μm) don Chimeric N-Terminus na Oxytocin Repotor. Carbetocin yana da damar bincike na badwartarwar bunmentrus. Carbetocin zai iya shiga cikin shingen kwakwalwar jini kuma yana da aiki mai kama da kunnawa ta hanyar kunna masu karɓar OWnttocin na Oxyttocin a cikin CNS.
Aiki
Carbetocin shine dogon-daci-dabi'ar oxyticin 8-peptide analog tare da kaddarorin agonist, da kuma ilimin likitanci suna kama da na Oxyttocin. Kamar Oxyttocin, Carbetocin ya yi rawar jiki ga masu karɓar ƙwayar cuta mai santsi, yana haifar da haɓakar igiyar ciki, ƙara haɓakar igiyar ciki, ƙara haɓakar igiyar ciki, yana ƙara haɓakar igiyar ciki, yana ƙaruwa da haɓakar asalinsu ta asali. Oxytocin Repcetror a cikin mahaifa ya ragu a cikin wanda bai ji ba, karuwa yayin daukar ciki, da kuma lokacin aiki. Saboda haka, Carbetocin bashi da tasiri a kan mahaifa mai ciki, amma yana da tasiri na kwangila na ciki a cikin mahaifa da kuma sabon mahaifa da sabon mahaifa.
Canza sarrafawa
Ana sarrafa canje-canje bisa ga tsarin. Dangane da tasirin da haɗari da tsananin ƙarfi, ana rarrabe canje-canje a matsayin manyan, ƙarami da rukunin yanar gizo. Canje-canje Site suna da ɗan ƙaramin tasiri akan aminci da ingancin samfurin, sabili da haka baya buƙatar amincewa da sanarwa ga abokin ciniki; Ƙananan canje-canje suna da matsakaici tasiri akan aminci da ingancin samfurin, kuma kuna buƙatar sanar da abokin ciniki; Manyan canje-canje suna da tasiri mafi girma akan aminci da ingancin samfurin, kuma buƙatar yarda da abokin ciniki.
Dangane da hanyar, ana farawa ne da canza aikace-aikacen canji wanda za'a iya bayyana cikakkun bayanai da hankali ga canji aka bayyana. Ana aiwatar da kimantawa akan aikace-aikacen, wanda aka yi ta canza matakan da ake amfani da su. A halin yanzu, an rarraba ikon canjin canji cikin manyan matakai, babban matakin da ƙarami. Bayan kimantawa da ya dace da kuma rarrabuwa, ya kamata mai kula da canjin Qa Manajan. An kashe tsarin canji bayan amincewa gwargwadon aikin. A ƙarshe an rufe ikon canjin bayan Qa ya tabbatar da sarrafawar canji. Idan ya shafi sanarwar abokin ciniki, ya kamata a sanar da abokin ciniki a hankali bayan an inganta shi da ikon canza
