Daptomycin 103060-53-3 don cututtukan cututtuka
Cikakken Bayani
| Suna | Saptomycin |
| Lambar CAS | 103060-53-3 |
| Tsarin kwayoyin halitta | C72H101N17O26 |
| Nauyi na kwayoyin | 1620.67 |
| Lambar Einecs | 600-389-2 |
| Mallaka | 202-204 ° C |
| Tafasa | 2078.2 ± 65.0 ° C (annabta) |
| Yawa | 1.45 ± 0.1 g / cm3 (annabta) |
| M hanya | 87 ℃ |
| Yanayin ajiya | Hatimi a bushe, adana a cikin injin daskarewa, kasa -20 ° C |
| Socighility | Methanol: Solraby5mg / ml |
| Acidarancin acid | (Pka) 4.00 ± 0.10 (annabta) |
| Fom | foda |
| Launi | mara launi don rauni |
Kwatanci
N- [1-oxodecyl) -l-trp-d-asn-l-asp -] - cyclo [4- ; N- [n-decanoyl-l-trp-d-asp -] - cyclo [3-Ala -3-ANA -3 Ecl Glutamyl-α, 2-dianao-γ-benzenebutanoicacid (13-4) Laconebutanoicacid (13-4) Laconebutanoancacid (13-4) Lacone; DapcinCinadession (ly146032)
Siffantarwa
A cikin maganin mayeka na maganin rigakafi shine maganin ƙwayar cuta ta cycopeptide tare da sabon tsari na ƙwayar ƙwayar cuta ta ƙwayar cuta ta ƙwayar ƙwayar ƙwayar halittu ta hanyar rikitarwa da jigilar amino acid. Sauya kaddarorin na Cytoplasmic na Cytoplasmic na iya rushe membrane na kwayoyin cuta na kwayoyin halitta kuma cikin hanzari ya kashe kwayar cuta mai kyau. Baya ga iyawar da ta dace da kwayar cuta ta kwayar cuta ta kwarai a asibiti, Dapactomycin ya fi mahimmanci ga nau'ikan warewar da suka nuna jingina ga Metheicillin, Vackacycin, da layi a cikin vitro. Yana da aiki mai iko, kuma wannan kadar yana da matukar mahimmanci a asibiti don rashin lafiyar marasa lafiya masu cutar. ESININOPHLIC huhun huhu ne mai wuya kuma mummunan cuta tare da bayyanar cututtuka ciki har da zazzabi, tari, gajiyayyen numfashi, da wahalar numfashi.
Antitbactara tasiri
Aptomycin yana da kyakkyawan aiki akan kwayoyin cuta masu tsayayya da cuta iri-iri, kamar Micrewa) tsayayyawar Staus (MRSA), da MTSA), da MTSA) mai tsoratarwa (MRSA). Micr.0625 ~ 1μg / ml don ƙwayoyin cuta, Mic = 2.5μg / ml don Intercoccus StrepylocyCuct, Mic = 2.5μg / ML don GMRBIA -Te ML 0.5 ~ 1μg / ml, da Mic na Shigara Juriya don glycopeeptide rigakafin rigakafi shine 1 ~ 2μg / ml.
