GnRH Antagonist Amfani da Peptides Synthesis
Cikakken Bayani
| NO | Kayayyaki | CAS No. | Aikace-aikace | Maɓallin Ingancin Maɓalli | ||||
| Tsafta | Isomer | Takamaiman kazanta | *Max1 | Danshi | ||||
| 1 | Fmoc-3-(2-naphthyl)-D-Ala-OH | 138774-94-4 | Yawancin samfurori | ≥99.0% | ≤0.2% | ≤0.3% | ≤0.3% | ≤1.0% |
| 2 | Ac-3-(2-naphthyl)-D-Ala-OH | 37440-01-0 | Yawancin samfurori | ≥99.0% | ≤0.2% | ≤0.3% | ≤0.3% | ≤1.0% |
| 3 | Fmoc-3-(3-pyridinyl)-D-Ala-OH | 142994-45-4 | Yawancin samfurori | ≥99.0% | ≤0.2% | ≤0.3% | ≤0.3% | ≤1.0% |
| 4 | Fmoc-4-chloro-D-Phe-OH | 142994-19-2 | Yawancin samfurori | ≥99.0% | ≤0.2% | ≤0.3% | ≤0.3% | ≤1.0% |
| 5 | Fmoc-D-Cit-OH | 200344-33-8 | Cetrorelix | ≥99.5% | ≤0.1% | ≤0.1% | ≤0.2% | ≤1.0% |
| 6 | Fmoc-D-Ala-OH.H2O | 79990-15-1 | Yawancin samfurori | ≥99.5% | ≤0.1% | ≤0.1% | ≤0.2% | ≤6.5% |
| 7 | Fmoc-D-Aph(tBuCbm) -OH | 1433975-21-3 | Dagarelix | ≥99.0% | ≤0.2% | ≤0.3% | ≤0.3% | ≤1.0% |
| 8 | Fmoc-D-Aph(Cbm) - OH | 324017-22-3 | Dagarelix | ≥99.0% | ≤0.2% | ≤0.3% | ≤0.3% | ≤1.0% |
| 9 | Fmoc-L-Aph (L-Hor) - OH | 1253282-31-3 | Dagarelix | ≥99.0% | ≤0.2% | ≤0.3% | ≤0.3% | ≤1.0% |
| 10 | Fmoc-L-Lys(iPr,Boc) -OH | 201003-48-7 | Dagarelix | ≥99.0% | ≤0.2% | ≤0.3% | ≤0.3% | ≤1.0% |
| 11 | Fmoc-N-Me-Tyr(tBu)-OH | 133373-24-7 | Abarelix | ≥99.0% | ≤0.2% | ≤0.3% | ≤0.3% | ≤1.0% |
| 12 | Fmoc-D-Asn(Trt)-OH | 180570-71-2 | Abarelix | ≥99.0% | ≤0.2% | ≤0.3% | ≤0.3% | ≤1.0% |
| 13 | Fmoc-HomoArg (Et) 2-OH.HCl | 1864003-26-8 | Ganirelix | ≥95.0% | ≤0.5% | ≤1.0% | ≤2.0% | ≤2.0% |
| 14 | Fmoc-D-HomoArg(Et)2-OH.HCl | 2098497-24-4 | Ganirelix | ≥95.0% | ≤0.5% | ≤1.0% | ≤2.0% | ≤2.0% |
| 15 | Fmoc-Lys (nicotinoyl) - OH | 252049-11-9 | Antide | ≥98.0% | ≤0.2% | ≤0.3% | ≤0.5% | ≤1.0% |
| 16 | Fmoc-D-Lys (nicotinoyl) - OH | 252049-12-0 | Antide | ≥98.0% | ≤0.2% | ≤0.3% | ≤0.5% | ≤1.0% |
* Max1 = Mafi ƙazanta mara sani
Sauran Alamomi:
Acetic acid: ≤0.02% (Duk samfuran)
- Ethyl Acetate: ≤0.5% (Duk samfuran)
- Barasa: ≤0.5% (Duk samfuran)
TOC da Gudanarwa
Ana kula da TOC da haɓakar manyan abubuwan samarwa da wuraren dawowa lokaci-lokaci.QC yana kula da TOC akan kowane mako.Ana sa ido kan ayyukan aiki akan layi kuma ana yin rikodin ma'aikacin tashar ruwa mai tsabta sau ɗaya kowane awa huɗu.Ana kula da ƙaddamarwa a farkon RO, RO na biyu, EDI da kuma jimlar dawowar tsarin rarrabawa.Ƙayyadaddun ƙayyadaddun ruwa mai tsafta yana cikin wuri kuma ya dace da ƙayyadaddun ƙayyadaddun bayanai wanda bai wuce 1.3 µs/cm a 25°C (USP).Don babban wadata da wuraren dawowa, cikakken gwaji.ana yin kowane mako, don sauran amfani da maki a cikin madauki na kewayawa, ana yin cikakken gwaji sau ɗaya kowane wata.Cikakken gwajin ya haɗa da haruffa, pH, nitrate, nitrite, ammonia, conductivity, TOC, abubuwan da ba sa canzawa, karafa masu nauyi, iyakokin ƙananan ƙwayoyin cuta da endotoxin na kwayan cuta.
