Ibutamoren mesylingara ribar nauyi na jiki, serum igf-1 da kuma matakai

Siffantarwa

Ibrramolen mesyling magani magani ne wanda ke aikata shi azaman mai iko, mai ɗorewa, m mai tsiro, mimicking aikin GH don tayar da kwayoyin halittun dabbobi.

Aiki

An nuna na fitowar sakin da kuma samar da matakan da aka samar da matakan plasma da yawa ciki har da factor mai girma 1 (IGF-1), amma bai shafi matakan cortisol ba. Yawan jiyya a halin yanzu suna ci gaba da rage matakan wadannan ayoyin, kamar su a cikin yara ko tsofaffi na ma'adinai, suna yin magani mai yawan ma'abota, da kuma yin jiyya mai mahimmanci ga tsofaffin tsofaffi. Hakanan yana canza metabolism na kitsen jiki, don haka yana iya samun aikace-aikace a cikin lura da kiba.

A cikin karatun Vivo

Ibutamoren mesylate (5 MG / kg / KG / KG / KG / yana haifar da karancin nauyin jiki na jiki kuma yana ƙaruwa da memori-1 da kuma matakan gh a cikin karnuka. Ibutamoren Mesyyling sakamakon babu mahimmanci a CSF IGF-1 ko GH matakai a ranakun 7 ko 15 na binciken. Yi amfani da mice tare da Kunna Tubalan GH Tubalan waɗannan garin Ibutamoren mesyling (50 μg). A cikin bugun ƙwanƙwasa, GH da Octreotide sun kasa hana hana Ibutamoren Mesyate Neurons. Harkokin baka na MK-0677 yana da alaƙa da ƙaruwa mai mahimmanci a cikin GH da IgF-i wadanda ake ci gaba da tsawon lokacin magani. Gwamnatin GHH ta biye bayan gwamnatin Mk-06777 ta ƙunshi Episodic yana ƙaruwa sama da iko. Mk-0677 yana ƙaruwa da perak gh maida hankali ne bayan gwamnatin baki. Mk-0677 mai iko ne mai iko ne wanda ya haifar da karuwa da kai tsaye, karuwar dadewa a cikin matakan gh lokacin da ake gudanar da baki ko IV