Ste-γ-Glu-AEEA-AEEA-OSU

Ste-γ-Glu-AEEA-AEEA-OSU

Ste-γ-Glu-AEEA-AEEA-OSU sinadari ne na roba mai haɗaɗɗiyar ƙwayar cuta wanda aka ƙera don isar da magunguna da aka yi niyya da haɗin gwiwar magungunan-magungunan (ADCs). Yana fasalta wutsiya ta stearoyl (Ste) hydrophobic, γ-glutamyl manufa motif, AEEA spacers don sassauci, da ƙungiyar OSu (NHS ester) don ingantaccen haɗin gwiwa.

 
Bincike & Aikace-aikace:

An yi amfani da shi a cikin haɗakar magunguna da aka yi niyya da ƙirar nanocarrier

Yana haɓaka hulɗar sel membrane da ɗaukar ƙwayoyi

Yana sauƙaƙe haɗe-haɗe na takamaiman wurin biya ga peptides, ƙwayoyin rigakafi, ko masu ɗaukar kaya

Siffofin Samfura (Rukunin Gentolex):

Babban tsabta, shirye-shiryen haɗin gwiwar NHS ester

Ya dace da nazarin halittu da bincike mai niyya

Ste-γ-Glu-AEEA-AEEA-OSU shine manufa don haɓaka tsarin isar da magunguna daidai.