Eptifibatide don lura da m jijiyoyin jini 188627-80-7
Cikakken Bayani
| Suna | EPTIFTAD |
| Lambar CAS | 188627-80-7 |
| Tsarin kwayoyin halitta | C35h49n11o9s2 |
| Nauyi na kwayoyin | 831.96 |
| Lambar Einecs | 641-366-7 |
| Yawa | 1.60 ± 0.1 g / cm3 (annabta) |
| Yanayin ajiya | Tufafin da aka rufe a bushe, adana a cikin injin daskarewa, a ƙarƙashin -15 ° C |
Kwatanci
Eptfibatidepatatusesalt; up-har-gly-cys-nh2 trp-pro-cys-nhar-trp-pro-glyy-NHAhargdwpc-Nh2 Nomethyl) -n2- (3-erpapto-1-ohoproropyl-l-lysylam-l-lysylamide; MPA1-Pro-Gly-Coys-NH2
Pletelet Glycoproprostotein afagonist
Etifibtide (Haɗin kai) wani sabon abu ne na polyet glycoprote Iib / IIAIA Reformor antetelet, wanda ke hana haduwa ta hanyar hade da hanyar haduwa ta Platelet. Idan aka kwatanta da wani monoclonal Abciximab, Eptifibatide na hanya yana da ƙarfi, mafi ƙayyadadden yabo ga GPIIB / IIIa saboda kasancewar kasancewar mai ɗaukar hoto mai ɗaukar hoto don maye gurbin arginine. Sabili da haka, ya kamata ya sami kyakkyawan warkewa a cikin aikin tsattsauran ra'ayi na cututtukan zuciya mai rauni. Pletellet glycopote IIB / IIIIIIA Receptor magunguna da yawa an inganta abubuwa da yawa, kuma a halin yanzu akwai nau'ikan shirye-shirye da a cikin cikin ƙasa-inical, Abciximab, Eptifibatitide da Tirofiban. ). Babu gogewa kaɗan a cikin amfani da Platelet Glycopote GPIIB / IIIIA receport agagonists a China, da magungunan da ake samu kuma suna da iyaka. Daya magani daya ne kawai, Tirofiban hydrochloride, yana kan kasuwa. Saboda haka, sabon pletelet glycopotote na IIB ya ci gaba. / IIIIA recetor masu adawa da juna sani. Epenfide na cikin gida shine samfurin kwaikwayon kwaikwayo wanda Chengdu Sici BIOLAM Pasotal Pasot Pasot pases Co., Ltd.
Rarrabuwa
Rarrabewar magungunan tsufa
An ɓoye magungunan tarin abubuwa a cikin rukuni uku: 1. Cyclooxygenase-1 (cox-1) masu hana, kamar asfirin. 2. Inhibit Haɗin Adin Adenosine Diphosphate (ADP), kamar Abciximab, da sauransu 3. Pletellor, Tickelet, Tirofibor, da sauransu. Masu karbar fansho, sababbi da aka samu da aka kiyaye su da ingantattun magunguna daga maganin gargajiya na kasar Sin.
