Ganirelix Aptide APPP
Cikakken Bayani
| Suna | Gasirelix Acetate |
| Lambar CAS | 123246-29-7 |
| Tsarin kwayoyin halitta | C80H113Cln18o13 |
| Nauyi na kwayoyin | 1570.34 |
Kwatanci
AC-DPAL-DPal-Ser-Tyr-Dhar Ganordix; Ganirelix Acetate USP / EP /
Siffantarwa
Ganirelix shine fili mai sauƙaƙe na roba, da gishiri mai gishiri, ganirelux Acetate ne (GNRH) maimaitawar hagonist. Tsarin amino acid shi ne: ac-d-2ca-d-3pal-d-3pal-d-3pal-d-3pal-d-et2) -pro-l-homoarg (9,10-et2) -pro-L-Umarg Ainihin asibiti, ana amfani dashi a mata ana tsammanin shirye-shiryen fasahar da aka kula da su don hana lalata ƙwayar ƙwayar cuta ta hanyar wannan sanadin. Magungunan suna da halaye na ƙasa da ƙananan halayen marasa kyau, yawan juna da juna, kuma yana da hujja a fili da irin magunguna a cikin aikin asibiti.
Mataki na magunguna
Pulsasile sakin Gonadotillin-sakin Hormone (GNRH) yana ƙarfafa tsarin kira da hasken fata na lh da f y. Mitar LH ta motsa a tsakiyar da marigayi maganganu masu yawa shine kimanin 1 a kowace awa. Wadannan ureses suna nunawa a cikin tashin hankali ya hau cikin Serum LH. A lokacin haila lokacin haila, wanda aka tsara sakin Gnrh yana haifar da karar lh. Middige Midterenuta na iya haifar da martani da yawa na ilimin sirri, ciki har da: ci gaba na Meocyte, da kuma ɗakunan ƙwaƙwalwar ƙwaƙwalwar ƙwayar cuta. Samuwar luteum lute yana haifar da matakan Progsterone na tashi, yayin da matakan estradiol suka fadi. Ganirelix Acetate wani Gnagontrastist ne na Gnagagonist wanda ya toshe Gnrh masu karbar rukisawa kan Pituitany Gonadotrophs da kuma masu biyo bayan hanyar watsa watsa hanyoyin. Yana fitar da saurin hanzari, soke rashi na gonadotropin. Rashin ingancin yanayin Ganirelix Acetate akan Pititary lh sirrinar ya fi ƙarfin cewa akan FR. Ganirelix Aceli ya kasa sanya saki na farko na gonadotropins, ya yi daidai da artagonm. Cikakken dawo da Pitiuitary LH da matakan Fsh sun faru ne a cikin sa'o'i 48 bayan an dakatar da Ganirelix Acetate.
