Ganirelix Acetate Peptide API

Sakin pulsatile na hormone mai sakin gonadotropin (GnRH) yana ƙarfafa kira da ɓoyewar LH da FSH.Yawan bugun jini na LH a cikin tsaka-tsaki da ƙarshen matakan follicular kusan 1 a cikin awa ɗaya.Wadannan bugun jini suna nunawa a cikin tashin lokaci-lokaci a cikin maganin LH.A lokacin tsakiyar lokacin haila, yawan sakin GnRH yana haifar da hauhawar LH.Ƙwararrun LH na tsakiyar haila na iya haifar da martanin ilimin lissafi da yawa, gami da: ovulation, resumption oocyte meiotic, da samuwar corpus luteum.Samuwar corpus luteum yana haifar da matakan progesterone na jini ya tashi, yayin da matakan estradiol ya fadi.Ganirelix acetate shine mai adawa da GnRH wanda ke toshe masu karɓar GnRH akan gonadotrophs na pituitary da hanyoyin canzawa na gaba.Yana haifar da hanzari, hanawa na hanawar gonadotropin.Sakamakon hanawa na ganirelix acetate akan ɓoyewar LH pituitary ya fi ƙarfin wannan akan FSH.Ganirelix acetate ya kasa haifar da sakin farko na gonadotropins na endogenous, daidai da antagonism.Cikakken dawo da matakan LH na pituitary da FSH ya faru a cikin awanni 48 bayan an daina ganirelix acetate.