Leuperorelin Acetate yana daidaita ɓoye ƙwararrun ƙwayoyin halittar gonadal
Cikakken Bayani
| Suna | Leuprorellin |
| Lambar CAS | 53714-56-056-0L6-0 |
| Tsarin kwayoyin halitta | C59H84N16O12 |
| Nauyi na kwayoyin | 1209.4 |
| Lambar Einecs | 633-395-9 |
| Takamaiman juyawa | D25 -31.7 ° (C = 1 a cikin 1% Acetic acid) |
| Yawa | 1.44 ± 0.1 g / cm3 (annabta) |
| Yanayin ajiya | -15 ° C |
| Fom | M |
| Acidarancin acid | (Pka) 9.82 ± 0.15 (annabta) |
| Sanarwar ruwa | Solumle cikin ruwa a 1mg / ml |
Kwatanci
LH-RHLEUPROLIDE;LEUPROLIDE;LEUPROLIDE(HUMAN);LEUPRORELIN;[DES-GLY10,D-LEU6,PRO-NHET9]-LUTEINIZINGHORMONE-RELEASINGHORMONEHUMAN;(DES-GLY10,D-LEU6,PRO -Nethet9) -luteerizormormone-set1dinghormormone, D-LEU6, Pro-Gly1eDhactFactor; [D-Gly1eDhactfactor;
Tasirin magunguna
Lafiyar, goselin, TrielRin, da Nafarelin, magunguna da yawa suna amfani da magunguna don maganin cutar sankara da cutar kansa da cutar kansa. (Ana kiranta azaman gnrh-da kwayoyi), Gnrh-da magunguna suna kama da tsarin zuwa Gnrh kuma gasa tare da Pituitary masu karɓa Gnrh. Wato, Gondotroppin ya sirri da bituuity ya ragu, wanda ke haifar da raguwa sosai a cikin jima'i horar da ovary.
Lauprorode ne Gonodotropin-sake fitarwa (GNRH) analog, peptide ya ƙunshi amino acid. Wannan samfurin zai iya hana aikin enituzytic, enzymes da kusancin Gnrh, kuma ayyukan inganta sakin Luteinary Hormone (LH) kusan sau 20 ne sau 20 kenan na Gnrh. Hakanan yana da tasirin ƙwararren mai ƙarfi akan Pituitary-Gonad fiye da GnrH. A cikin farkon mataki, follicle motsa jiki (FSH), lh, Estrogen ko Androgen na ɗan lokaci na ɗan lokaci, sakamakon an hana shi, sakamakon dogaro da ayoyin jima'i. Cututtukan jima'i (kamar cutar sankarau, Endometeroosis, da sauransu) suna da tasirin warkewa.
A halin yanzu, Acetate gishirin na Leuperide akayi amfani da asibiti ne mafi fili a asibiti, saboda aikin leuprolite ya fi kwanciyar hankali a dakin da zazzabi. Ya kamata a jefar da ruwa. Ana iya amfani dashi don maganin castometriososis da igiyar ciki na cutar kansa, na tsakiya, da kuma cututtukan mahaifa wanda yake contraindicated ko rashin aiki na al'ada don maganin ƙwayar cuta na al'ada. Hakanan za'a iya amfani dashi azaman sifar Endometrial, wanda zai iya bakin ciki a hankali Endometrium, rage edema, kuma rage wahalar tiyata.
