Linaclotide don rikitarwa na ciki 8511999-59
Cikakken Bayani
| Suna | Linaclotide |
| Lambar CAS | 8511999-59-2 |
| Tsarin kwayoyin halitta | C59H79N15O21S6 |
| Nauyi na kwayoyin | 152,74 |
Kwatanci
Linacllotide; Linaclotide; Linaellotideacetate; Linaelotide; Cy-14; Lantarki; L-αlotinyl-L-α -L-cysteinyl-l-cyspayl-l-poryl-l-cysteinyl-L-cyseinyl-, 1 → 6), (5 →) -Tris (disulfode)
Siffantarwa
Linaclotide, tsarin peptide na roba dauke da amino acid 17, yana da dangantaka da ƙwayoyin cuta na Gin-C (gugyate) cyclase-c) cyclasorist na yau da kullun (is-c) da maƙarƙashiya (CIC) a cikin manya.
Kayan sunadarai
Linaclotide shine fari don kashe-farin amorphous foda; Dan kadan mai narkewa a cikin ruwa da ruwan kifin ruwan chlorious (0.9%).
Yadda yake aiki
Linaclotide ne mai gina ctinclase-C Repopor Agonist (GCCA) tare da duka ayyukan Analgesic da na encrinine. Dukkanin Linaclotide da Metaboling Metabolite na iya ɗaure shi zuwa ga Gany Cyclese-C (GC-C) Mai karɓar a kan farfajiyar ƙwayoyin ƙwaƙwalwar ciki. A cikin samfuran dabbobi, Linaclotide yana rage ciwon ciki da ƙara yawan jigilar ciki ta hanyar kunnawa GC-C, kuma a cikin mutane, da miyagun ƙwayoyi suna kara yawan jigilar mulkin mallaka. Sakamakon aikin kunnawa GC-C ya ƙaru cikin karkara da kuma cgmpular cgmp (cyclic Guanosirate) maida hankali). Cikakken cgmpular cgmpular na iya rage ayyukan jijiyoyin jijiya da rage zafin da ke ciki a cikin dabbobin. CGMPLULLULLULUZE CGMP na iya haɓaka ɓoyayyen chloride da Bicarbonate a cikin ƙaramin hanji ta hanyar kunna CFR (Sirrin Cinstic Myprombrator), wanda ƙarshe ya haifar da haɓaka ƙananan ƙwayar hanji da saurin ƙaramin hanyar shiga.
Faq
Kuna da tabbacin aminci da amintaccen samar da kayayyaki?
Ee, koyaushe muna amfani da kayan aikin fitarwa. Haka nan muna amfani da kayan haɗi na musamman don kayan haɗari da ingantattun wuraren ajiya mai sanyi don abubuwan da ke cikin zafin jiki. Abubuwan ƙirar ƙwararru da abubuwan da ba daidaitattun bukatun na iya haifar da ƙarin caji ba.
Yaya game da kudaden jigilar kaya?
Farashin jigilar kaya ya dogara da hanyar da kuka zaɓi don samun kayan. Express shine yawanci da sauri amma kuma mafi tsada hanya. Ta hanyar jirgin ruwa na teku shine mafi kyawun mafita don manyan abubuwa. Daidai farashin sufuri Zamu iya ba ku idan mun san cikakkun bayanai na adadin, nauyi da hanya. Da fatan za a tuntuɓe mu don ƙarin bayani.
